Description
Product Characteristics: Adapter protein TKS5 antibody, Five SH3 domain-containing protein antibody, SH3 and PX domain-containing protein 2A antibody, SH3 multiple domains protein 1 antibody, Sh3md1 antibody, Sh3pxd2a antibody, SPD2A_HUMAN antibody, TKs5 antibody, Tyrosine kinase substrate with five SH3 domains antibody
Target Information: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide (By similarity)